|
KMID : 0360120100320050396
|
|
Journal of the Korean Society of Maxillofacial Plastic Reconstructive Surgeons
2010 Volume.32 No. 5 p.396 ~ p.405
|
|
|
The Effect of ER:YAG Laser & ER,CR:YSGG Laser on the Tissue of the Inflammation-Induced Mouse
|
|
Park Tae-Il
Lee Hyung-Seok
Lee Hee-Jong
Chae Chang-Hoon
Lee Young-Joo
Byeon kwang-Seob
Hong Soon-Min
Choi Mee-Ra
Park Jun-Woo
|
|
|
Abstract
|
|
|
Purpose:This study was performed to find out the effects of the Er:YAG laser (Key Laser) & Er,Cr:YSGG laser (Water Laser) on inflammatory tissues .
Methods:It was performed on about 20 g, 6 weeks male ICR mouses. They were grouped into the control (negative), the inflammation induced ‘control’(positive), Er,Cr:YSGG laser exposured group after inducing inflammation, Er:YAG lasere exposured group after inducing inflammation each 15 mouses. The mouses were applicated 0.5% DNFB 1 cc on ear skin twice a day for 4 days until symptom expression. After laser exposure, ear tissues were extracted and defined gene expression by RT-PCR. Then, tissue staining, lymphocytes observation, electromicroscophic laboratory were carried out.
Results:Interleukin-1βwas expressed much less in the A-laser exposed group. Interleukin-1β& Tumor Necrosis Factor-αwere expressed 7 times lesser in the A-laser exposed group. The number of Lymphocytes related to inflammation was decreased rapidly in the A-laser exposed group in vivo. he number of cavity recovered normal was a little bigger in the A-laser exposed group after 5 days.
Conclusions: The expression of IL-1β& TNF-α, hitologic change, observation with electron microscope shows that Erbium laser exposure causes lesser inflammation with A-laser rather than B-laser.
|
|
|
KEYWORD
|
|
|
Laser therapy, IL-1β& TNF-α, Mice, Electron microscope
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
 
|
|